Objective: The understanding of the microbial ecology is directly dependant upon involved factors which promote the colonization by the bacterial microflora. Disruption of the bacterial barrier function afforded by the predominant microflora can lead to colonization by pathogenic or opportunistic pathogenic species. Our study focuses on the microbial profile of the intestinal flora in healthy patients and in patients submitted to ozone therapy. Ozone is a strong antimicrobial agent against bacteria, fungi, viruses, protozoa and fungi. Inactivation of bacteria by ozone, seem to be a complex not yet elucidated processes, especially in the sector of human therapy.
Methods: Our study involves 15 healthy adults and 10 patients with dysbiosis which received ozone therapy. Ozone was given for treatment of microbial disbyosis in the intestine associated to different disease states.
Results: Staphycoccus coagulase(-) were predominant in all studied healthy adults. Staphylocoocus levels seem to decrease after ozone treatment. Specifically, following ozone treatment pathogenic Staphylococcal species such as S.aureus, were completely absent in all cases. Species variation and levels of isolated Staphylococcus were always inferior under ozone treatment.
Conclusions: Other factors or microbial antagonism seem to be crucial in the microbial colonization. Constructively, effect of ozone for patients treatment seems to be beneficial in cases of intestinal dysbiosis in cases where S. aureus dominates, but ozone must be applied with prudence estimating the global profit of the patient as ozone excess can guide to formation of free radicals or disequilibrium of the global intestinal flora.