Aim of study is evaluation of therapeutic effect of Antoxide in complex treatment of parodont and mouth cavity mucous membrane diseases.
Materials and methods. The study involved 58 patients, aged 19 and 55, including 13 patients with mouth cavity candidosis and 45 with parodont inflammatory diseases. Patients with candidosis were categorized as main (1st) and control (2nd ) groups. The 1st group (37 patients) was prescribed to take Antoxide. The 2nd group patients (21 patients) were treated without Antoxide.
Results. Bactericide effect of Antoxide was observed in vitro in regard of the following microbes: Staphylococcos aureus, Escherihia coli, Pseudomonas aeruginosa, Candida albicans that were derived from patients with inflammatory diseases. Our observation has shown that the bacteria placed in appropriate nourishment environments after 24-hour contact with Antoxode in test-tubes demonstrated no more growth. Permanent growth could only be observed in case of placing bacteria from control test-tube with physiological solution. That is evidence of high survival ability of the observed bacteria. For patient treatment in experiment the Antoxide in 100%, 50% and 25% solutions were used. The results demonstrate the strong bactericide effect of Antoxide on the observed bacteria species. Dynamics of subjective feelings, the clinical chart of diseases and lab analyses of patients with mouth cavity candidosis and parodont inflammatory diseases were taken into consideration.
Conclusion. Clinical and laboratory data of study has shown the highest effectiveness of Antoxide in complex treatment of parodont inflammatory and infection mouth cavity mucous membrane diseases.